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Which of the Following Is Not Limited to the Synthesis

Question 12

Multiple Choice

Which of the following is not limited to the synthesis of primary amines (R-NH2 or Ar-NH2) (i.e.,which,if any,can be used to make 2° or 3° amines) ?


A) Gabriel synthesis
B) Reduction of amides with LAH
C) Hofmann rearrangement
D) Reduction of nitriles with LAH
E) Reduction of nitro groups with Fe/HCl

Correct Answer:

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