Deck 12: The Trace Elements

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سؤال
Which of the following is NOT a good source of heme iron?

A)Beef
B)Chicken
C)Salmon
D)Spinach
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سؤال
Identify the most accurate statement regarding copper.

A)Copper deficiency usually causes iron-deficiency anemia.
B)Copper deficiency may result in zinc deficiency.
C)High copper intake can cause osteoporosis.
D)Copper excess may cause changes in hair color.
سؤال
Zinc deficiency in Iranian and Egyptian men occurred because:

A)they did not eat meat.
B)the diet was low in zinc since local soils were low in zinc.
C)they consumed diets high in animal protein,which inhibits zinc absorption.
D)phytates in the diet bound zinc,decreasing its bioavailability.
سؤال
Which is the true statement about iron loss?

A)When red blood cells die,the iron in the cells is excreted.
B)Most loss of iron from the body is associated with blood loss.
C)There is significant loss of iron through the urinary tract.
D)Iron from red blood cells binds to calcium and is excreted through the large intestine.
سؤال
One form of the enzyme superoxide dismutase (SOD),which has antioxidant properties,contains the trace element __________.

A)iron
B)copper
C)sulfur
D)sodium
سؤال
The symptoms of zinc deficiency include all of the following EXCEPT:

A)hair loss.
B)impaired reproduction.
C)anemia.
D)reduced immune function.
سؤال
_______________ is an inherited condition that causes individuals to absorb and accumulate too much iron.

A)Hemochromatosis
B)Hematocrit absorption syndrome
C)Hyperferritosis
D)Reverse anemia
سؤال
Which of the following is NOT a true statement?

A)Cooking in iron skillets can provide dietary iron.
B)Vitamin C enhances iron absorption.
C)Phytates in cereal enhance the absorption of iron.
D)Calcium supplements decrease iron absorption.
سؤال
Which is the most sensitive indicator of iron stores in the body?

A)Ferritin
B)Hematocrit
C)Hemoglobin
D)Transferrin
سؤال
When the intake of __________ is high,copper absorption into the blood is inhibited.

A)iodine
B)fluoride
C)chromium
D)zinc
سؤال
All of the following are adequate sources of nonheme iron EXCEPT:

A)apples.
B)enriched white rice.
C)garbanzo beans.
D)spinach.
سؤال
Which of the following would NOT enhance absorption of the iron found in supplements?

A)Consuming the supplement with a meal containing beef
B)Taking it with a calcium supplement
C)Taking the supplement with a meal containing fish
D)Consuming it with orange juice
سؤال
Which statement about zinc toxicity is FALSE?

A)It can lower HDL cholesterol.
B)It may occur from food and beverage contamination by galvanized containers.
C)Zinc toxicity interferes with the function of iron in superoxide dismutase.
D)It can decrease immune function.
سؤال
Which of the following groups is at risk for zinc deficiency in the United States?

A)Children aged 1-3 years
B)Adults older than 71 years of age
C)Adolescent boys
D)All of the above
سؤال
Which of the following is a true statement about iron requirements?

A)The RDA for young adult women is higher than the RDA young adult men.
B)For adolescents 14 to 18 years-of-age,the RDA is the same for males and females.
C)Iron requirements increase after menopause.
D)Babies should not be fed iron-containing formulas,because of the risk of toxicity.
سؤال
Iron is a component of the protein,______ that binds and transports oxygen in the bloodstream.

A)ferritin
B)albumin
C)hemoglobin
D)myoglobin
سؤال
The trace minerals are difficult to study in humans because:

A)some of them are required in such small amounts that environmental contamination can obscure experimental results.
B)they are so small,they are difficult to identify.
C)they are required in such small amounts that deficiencies do not occur.
D)biological tests are imprecise.
سؤال
Iron stores that are higher than normal but not at a toxic level may be associated with:

A)an increased risk of cancer and heart disease.
B)hyper-hemoglobinemia.
C)an improved immune system.
D)increased stamina and endurance.
سؤال
Lack of which trace element is the most common nutritional deficiency worldwide?

A)Copper
B)Zinc
C)Iron
D)Iodine
سؤال
Which of the following is a copper-containing plasma protein that converts iron to a form that can be transported and stored?

A)Ceruloplasmin
B)Ferritin
C)Hemoglobin
D)Transferrin
سؤال
The following are physiologic roles of copper EXCEPT:

A)connective tissue synthesis.
B)maintenance of heart muscle.
C)normal sexual development.
D)functioning of the central nervous system.
سؤال
Which of the following is an excellent source of selenium?

A)Salmon
B)Kiwi
C)Potato
D)Drinking water
سؤال
Which mineral protects against oxidative damage and also helps synthesize thyroid hormone?

A)Copper
B)Manganese
C)Selenium
D)Zinc
سؤال
Which statement about manganese toxicity is FALSE?

A)Toxic levels can occur in mineworkers exposed to manganese dust.
B)Manganese toxicity damages the nervous system.
C)Manganese toxicity is not the result of eating manganese-containing foods.
D)Manganese toxicity is a common cause of birth defects.
سؤال
Which of the following statements about Keshan disease is FALSE?

A)A virus appears to be involved.
B)It causes an enlarged heart and poor heart function.
C)Middle aged men are most at risk.
D)Keshan disease occurred in areas of China where soil selenium is very low.
سؤال
Copper deficiency is most likely to occur in:

A)pre-term infants.
B)children aged 1-3.
C)adolescents.
D)the elderly.
سؤال
High intakes of zinc stimulate the synthesis of _____________ in the mucosal cells.

A)ferritin
B)metallothionein
C)transferrin
D)zinc oxide dismutase
سؤال
Proteins containing selenium as a component of their amino acids are called:

A)glutathione peroxidases.
B)selenoenzymes.
C)selenoproteins.
D)superoxide dismutases.
سؤال
Which of the following statements is true regarding copper absorption?

A)Zinc promotes the absorption of copper.
B)About 80% of copper is absorbed.
C)Vitamin C enhances copper absorption.
D)By inhibiting zinc absorption,phytates may enhance the copper absorption.
سؤال
Which statement regarding antioxidant supplements is FALSE?

A)Some antioxidant supplements can actually enhance oxidation.
B)The optimum dose of each antioxidant is unknown.
C)Supplements cannot replace the benefits of eating antioxidant-rich foods.
D)Antioxidant enzyme supplements have been shown to boost defenses.
سؤال
Which statement is FALSE regarding the function of zinc in the body?

A)Zinc is a cofactor for many enzymes.
B)Zinc is needed for development of sex organs.
C)Zinc is needed for growth and tissue repair.
D)Zinc is needed for synthesis of vitamin E.
سؤال
The best dietary sources of manganese are:

A)fruits and vegetables.
B)nuts and whole grains.
C)meats.
D)dairy products.
سؤال
Which is NOT a plentiful source of zinc?

A)Beef
B)Refried beans
C)Saltine crackers
D)Yogurt
سؤال
Manganese homeostasis is maintained through:

A)excretion by the kidneys.
B)no controlled process.
C)regulation of absorption and excretion in the bile.
D)competition with other minerals.
سؤال
Iodine deficiency during pregnancy may cause ____________ in the offspring.

A)cretinism
B)neural tube defects
C)fetal goiter syndrome
D)hypoglycemia
سؤال
Which of the following is the poorest source of iodine?

A)Apricots
B)Milk
C)Shrimp
D)Iodized salt
سؤال
Iodine deficiency often causes an enlarged thyroid gland resulting in:

A)blockage of arteries leading to the heart.
B)a Dowager's hump.
C)a goiter.
D)shortness of breath.
سؤال
In most people,taking selenium supplements to increase intake over the RDA:

A)will protect against environmental pollutants.
B)will prevent heart disease.
C)will not provide any additional benefits.
D)will slow the aging process.
سؤال
A low selenium diet has been most highly associated with:

A)arthritis.
B)cancer.
C)dementia.
D)diabetes.
سؤال
The primary role of iodine in the body is:

A)as an antioxidant.
B)as a cofactor in hemoglobin synthesis.
C)as a component of thyroid hormones.
D)participation in carbohydrate metabolism
سؤال
Molybdenum is required for all of the following EXCEPT:

A)the metabolism of sulfur containing amino acids.
B)the production of uric acid.
C)the synthesis of collagen.
D)the metabolism of nitrogen containing compounds in RNA and DNA.
سؤال
Chromium is thought to work by:

A)binding to insulin.
B)slowing the absorption of glucose.
C)interacting with the insulin receptor.
D)stimulating the pancreas.
سؤال
The richest source(s)of copper in the diet is (are):

A)organ meats such as liver and kidney.
B)brewer's yeast.
C)avocados.
D)chicken and turkey.
سؤال
Which statement about overt chronic chromium deficiency is correct?

A)It may in part explain the obesity epidemic in the US.
B)It is common in the U.S.since so many processed foods are consumed.
C)Overt chronic chromium deficiency may occur in malnourished children.
D)Chromium deficiency results in high blood pressure and increased risk of stroke.
سؤال
Of the following,the best source of chromium is:

A)dairy.
B)whole grains.
C)vegetables.
D)fruits.
سؤال
Most of the fluoride in the U.S.comes from:

A)drinking water and toothpaste.
B)dark green and yellow vegetables.
C)tea.
D)seafood and treated salt.
سؤال
___________ is not a component of an antioxidant enzyme.

A)Copper
B)Iodine
C)Selenium
D)Zinc
سؤال
Iodine deficiency during childhood and adolescence has been known to cause:

A)premature baldness.
B)impaired mental function.
C)cancer risk in later life.
D)sudden death.
سؤال
Fluoride has shown to be most effective in preventing:

A)colon cancer.
B)dental caries.
C)osteomalacia.
D)obesity.
سؤال
Which is NOT a factor in determining the rates of iron absorption?

A)Blood glucose levels
B)Levels of iron stores
C)Presence of vitamin C in foods
D)Form of iron ingested
سؤال
Which statement about chromium supplementation is the most accurate?

A)Supplementation may improve the symptoms of type 2 diabetes.
B)Chromium supplementation increases lean body mass.
C)It leads to weight loss.
D)It may improve athletic performance.
سؤال
Which statement about fluoride is FALSE?

A)Fluoride is poorly absorbed,with only ~20% transported across the intestine.
B)Calcium containing foods decrease fluoride absorption.
C)Fluoridated water typically contains 0.7-1.2 ppm fluoride.
D)Fluoride has the greatest effect on caries prevention before age 13.
سؤال
____________is needed to activate enzymes and in the production of uric acid.

A)Chromium
B)Molybdenum
C)Selenium
D)Zinc
سؤال
What is the function of hemoglobin in the body?
سؤال
Substances that interfere with the utilization of iodine or with the function of the thyroid gland are called:

A)thyroxin interference aggregates.
B)goitrogens.
C)homeostatic decoupling agents.
D)cretinoids.
سؤال
Marginal chromium deficiency has been linked to:

A)breast cancer.
B)polio.
C)strokes.
D)type 2 diabetes.
سؤال
The poorest source of fluoride among the following is:

A)toothpaste.
B)foods cooked with Teflon.
C)tea.
D)pork.
سؤال
Of the following,_______ is (are)the best source of zinc.

A)apples
B)refined grains
C)chocolate
D)red meat
سؤال
Excess fluoride consumption may cause:

A)arthritis.
B)diarrhea.
C)hives and dermatitis.
D)mottled teeth.
سؤال
___________ is a component of the antioxidant enzyme gluthathione peroxidase.

A)Molybdenum
B)Nickel
C)Selenium
D)Boron
سؤال
What are common physiologic functions of manganese?
سؤال
For which population groups is iron deficiency most likely? Why?
سؤال
What role does zinc play in reducing the prevalence and severity of the common cold?
سؤال
Why is fluoride commonly added to drinking water?
سؤال
What role does soil selenium content play in Keshan Disease?
سؤال
Why are adequate intakes of iodine essential to good health? What are characteristics of iodine deficiencies?
سؤال
What is the role of selenium in Keshan disease?
سؤال
What factors enhance iron absorption? What are factors that interfere with iron absorption?
سؤال
Which population groups would benefit the most from fluoridation of the water? Why?
سؤال
What factors influence copper absorption into the body?
سؤال
What are good dietary sources of iodine?
سؤال
What are consequences of a zinc deficient diet?
سؤال
How can a person increase their intake of dietary iron?
سؤال
What are the best food sources of zinc?
سؤال
What role does chromium play in the body?
سؤال
What is a goitrogen? What are common sources?
سؤال
How is iron transported in the blood?
سؤال
How iron levels maintained in the body?
سؤال
If the initiative does not pass and fluoride is not added to the drinking water,what are other means by which the dental health of children in the community could be protected?
سؤال
The water supply in the small city where you live is not fluoridated.There is an initiative on an upcoming ballot to add fluoride in small amounts to the water in order to decrease dental caries.What is your opinion on the issue?
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ملء الشاشة (f)
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Deck 12: The Trace Elements
1
Which of the following is NOT a good source of heme iron?

A)Beef
B)Chicken
C)Salmon
D)Spinach
D
2
Identify the most accurate statement regarding copper.

A)Copper deficiency usually causes iron-deficiency anemia.
B)Copper deficiency may result in zinc deficiency.
C)High copper intake can cause osteoporosis.
D)Copper excess may cause changes in hair color.
A
3
Zinc deficiency in Iranian and Egyptian men occurred because:

A)they did not eat meat.
B)the diet was low in zinc since local soils were low in zinc.
C)they consumed diets high in animal protein,which inhibits zinc absorption.
D)phytates in the diet bound zinc,decreasing its bioavailability.
D
4
Which is the true statement about iron loss?

A)When red blood cells die,the iron in the cells is excreted.
B)Most loss of iron from the body is associated with blood loss.
C)There is significant loss of iron through the urinary tract.
D)Iron from red blood cells binds to calcium and is excreted through the large intestine.
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5
One form of the enzyme superoxide dismutase (SOD),which has antioxidant properties,contains the trace element __________.

A)iron
B)copper
C)sulfur
D)sodium
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6
The symptoms of zinc deficiency include all of the following EXCEPT:

A)hair loss.
B)impaired reproduction.
C)anemia.
D)reduced immune function.
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7
_______________ is an inherited condition that causes individuals to absorb and accumulate too much iron.

A)Hemochromatosis
B)Hematocrit absorption syndrome
C)Hyperferritosis
D)Reverse anemia
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8
Which of the following is NOT a true statement?

A)Cooking in iron skillets can provide dietary iron.
B)Vitamin C enhances iron absorption.
C)Phytates in cereal enhance the absorption of iron.
D)Calcium supplements decrease iron absorption.
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9
Which is the most sensitive indicator of iron stores in the body?

A)Ferritin
B)Hematocrit
C)Hemoglobin
D)Transferrin
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10
When the intake of __________ is high,copper absorption into the blood is inhibited.

A)iodine
B)fluoride
C)chromium
D)zinc
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11
All of the following are adequate sources of nonheme iron EXCEPT:

A)apples.
B)enriched white rice.
C)garbanzo beans.
D)spinach.
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12
Which of the following would NOT enhance absorption of the iron found in supplements?

A)Consuming the supplement with a meal containing beef
B)Taking it with a calcium supplement
C)Taking the supplement with a meal containing fish
D)Consuming it with orange juice
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13
Which statement about zinc toxicity is FALSE?

A)It can lower HDL cholesterol.
B)It may occur from food and beverage contamination by galvanized containers.
C)Zinc toxicity interferes with the function of iron in superoxide dismutase.
D)It can decrease immune function.
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14
Which of the following groups is at risk for zinc deficiency in the United States?

A)Children aged 1-3 years
B)Adults older than 71 years of age
C)Adolescent boys
D)All of the above
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15
Which of the following is a true statement about iron requirements?

A)The RDA for young adult women is higher than the RDA young adult men.
B)For adolescents 14 to 18 years-of-age,the RDA is the same for males and females.
C)Iron requirements increase after menopause.
D)Babies should not be fed iron-containing formulas,because of the risk of toxicity.
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16
Iron is a component of the protein,______ that binds and transports oxygen in the bloodstream.

A)ferritin
B)albumin
C)hemoglobin
D)myoglobin
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17
The trace minerals are difficult to study in humans because:

A)some of them are required in such small amounts that environmental contamination can obscure experimental results.
B)they are so small,they are difficult to identify.
C)they are required in such small amounts that deficiencies do not occur.
D)biological tests are imprecise.
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18
Iron stores that are higher than normal but not at a toxic level may be associated with:

A)an increased risk of cancer and heart disease.
B)hyper-hemoglobinemia.
C)an improved immune system.
D)increased stamina and endurance.
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19
Lack of which trace element is the most common nutritional deficiency worldwide?

A)Copper
B)Zinc
C)Iron
D)Iodine
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20
Which of the following is a copper-containing plasma protein that converts iron to a form that can be transported and stored?

A)Ceruloplasmin
B)Ferritin
C)Hemoglobin
D)Transferrin
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21
The following are physiologic roles of copper EXCEPT:

A)connective tissue synthesis.
B)maintenance of heart muscle.
C)normal sexual development.
D)functioning of the central nervous system.
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22
Which of the following is an excellent source of selenium?

A)Salmon
B)Kiwi
C)Potato
D)Drinking water
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23
Which mineral protects against oxidative damage and also helps synthesize thyroid hormone?

A)Copper
B)Manganese
C)Selenium
D)Zinc
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24
Which statement about manganese toxicity is FALSE?

A)Toxic levels can occur in mineworkers exposed to manganese dust.
B)Manganese toxicity damages the nervous system.
C)Manganese toxicity is not the result of eating manganese-containing foods.
D)Manganese toxicity is a common cause of birth defects.
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25
Which of the following statements about Keshan disease is FALSE?

A)A virus appears to be involved.
B)It causes an enlarged heart and poor heart function.
C)Middle aged men are most at risk.
D)Keshan disease occurred in areas of China where soil selenium is very low.
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26
Copper deficiency is most likely to occur in:

A)pre-term infants.
B)children aged 1-3.
C)adolescents.
D)the elderly.
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27
High intakes of zinc stimulate the synthesis of _____________ in the mucosal cells.

A)ferritin
B)metallothionein
C)transferrin
D)zinc oxide dismutase
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28
Proteins containing selenium as a component of their amino acids are called:

A)glutathione peroxidases.
B)selenoenzymes.
C)selenoproteins.
D)superoxide dismutases.
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29
Which of the following statements is true regarding copper absorption?

A)Zinc promotes the absorption of copper.
B)About 80% of copper is absorbed.
C)Vitamin C enhances copper absorption.
D)By inhibiting zinc absorption,phytates may enhance the copper absorption.
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30
Which statement regarding antioxidant supplements is FALSE?

A)Some antioxidant supplements can actually enhance oxidation.
B)The optimum dose of each antioxidant is unknown.
C)Supplements cannot replace the benefits of eating antioxidant-rich foods.
D)Antioxidant enzyme supplements have been shown to boost defenses.
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31
Which statement is FALSE regarding the function of zinc in the body?

A)Zinc is a cofactor for many enzymes.
B)Zinc is needed for development of sex organs.
C)Zinc is needed for growth and tissue repair.
D)Zinc is needed for synthesis of vitamin E.
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32
The best dietary sources of manganese are:

A)fruits and vegetables.
B)nuts and whole grains.
C)meats.
D)dairy products.
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33
Which is NOT a plentiful source of zinc?

A)Beef
B)Refried beans
C)Saltine crackers
D)Yogurt
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34
Manganese homeostasis is maintained through:

A)excretion by the kidneys.
B)no controlled process.
C)regulation of absorption and excretion in the bile.
D)competition with other minerals.
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35
Iodine deficiency during pregnancy may cause ____________ in the offspring.

A)cretinism
B)neural tube defects
C)fetal goiter syndrome
D)hypoglycemia
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36
Which of the following is the poorest source of iodine?

A)Apricots
B)Milk
C)Shrimp
D)Iodized salt
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37
Iodine deficiency often causes an enlarged thyroid gland resulting in:

A)blockage of arteries leading to the heart.
B)a Dowager's hump.
C)a goiter.
D)shortness of breath.
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38
In most people,taking selenium supplements to increase intake over the RDA:

A)will protect against environmental pollutants.
B)will prevent heart disease.
C)will not provide any additional benefits.
D)will slow the aging process.
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39
A low selenium diet has been most highly associated with:

A)arthritis.
B)cancer.
C)dementia.
D)diabetes.
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40
The primary role of iodine in the body is:

A)as an antioxidant.
B)as a cofactor in hemoglobin synthesis.
C)as a component of thyroid hormones.
D)participation in carbohydrate metabolism
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41
Molybdenum is required for all of the following EXCEPT:

A)the metabolism of sulfur containing amino acids.
B)the production of uric acid.
C)the synthesis of collagen.
D)the metabolism of nitrogen containing compounds in RNA and DNA.
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42
Chromium is thought to work by:

A)binding to insulin.
B)slowing the absorption of glucose.
C)interacting with the insulin receptor.
D)stimulating the pancreas.
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43
The richest source(s)of copper in the diet is (are):

A)organ meats such as liver and kidney.
B)brewer's yeast.
C)avocados.
D)chicken and turkey.
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44
Which statement about overt chronic chromium deficiency is correct?

A)It may in part explain the obesity epidemic in the US.
B)It is common in the U.S.since so many processed foods are consumed.
C)Overt chronic chromium deficiency may occur in malnourished children.
D)Chromium deficiency results in high blood pressure and increased risk of stroke.
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45
Of the following,the best source of chromium is:

A)dairy.
B)whole grains.
C)vegetables.
D)fruits.
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46
Most of the fluoride in the U.S.comes from:

A)drinking water and toothpaste.
B)dark green and yellow vegetables.
C)tea.
D)seafood and treated salt.
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47
___________ is not a component of an antioxidant enzyme.

A)Copper
B)Iodine
C)Selenium
D)Zinc
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48
Iodine deficiency during childhood and adolescence has been known to cause:

A)premature baldness.
B)impaired mental function.
C)cancer risk in later life.
D)sudden death.
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49
Fluoride has shown to be most effective in preventing:

A)colon cancer.
B)dental caries.
C)osteomalacia.
D)obesity.
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50
Which is NOT a factor in determining the rates of iron absorption?

A)Blood glucose levels
B)Levels of iron stores
C)Presence of vitamin C in foods
D)Form of iron ingested
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51
Which statement about chromium supplementation is the most accurate?

A)Supplementation may improve the symptoms of type 2 diabetes.
B)Chromium supplementation increases lean body mass.
C)It leads to weight loss.
D)It may improve athletic performance.
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52
Which statement about fluoride is FALSE?

A)Fluoride is poorly absorbed,with only ~20% transported across the intestine.
B)Calcium containing foods decrease fluoride absorption.
C)Fluoridated water typically contains 0.7-1.2 ppm fluoride.
D)Fluoride has the greatest effect on caries prevention before age 13.
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53
____________is needed to activate enzymes and in the production of uric acid.

A)Chromium
B)Molybdenum
C)Selenium
D)Zinc
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54
What is the function of hemoglobin in the body?
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55
Substances that interfere with the utilization of iodine or with the function of the thyroid gland are called:

A)thyroxin interference aggregates.
B)goitrogens.
C)homeostatic decoupling agents.
D)cretinoids.
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56
Marginal chromium deficiency has been linked to:

A)breast cancer.
B)polio.
C)strokes.
D)type 2 diabetes.
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57
The poorest source of fluoride among the following is:

A)toothpaste.
B)foods cooked with Teflon.
C)tea.
D)pork.
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58
Of the following,_______ is (are)the best source of zinc.

A)apples
B)refined grains
C)chocolate
D)red meat
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59
Excess fluoride consumption may cause:

A)arthritis.
B)diarrhea.
C)hives and dermatitis.
D)mottled teeth.
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60
___________ is a component of the antioxidant enzyme gluthathione peroxidase.

A)Molybdenum
B)Nickel
C)Selenium
D)Boron
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61
What are common physiologic functions of manganese?
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62
For which population groups is iron deficiency most likely? Why?
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63
What role does zinc play in reducing the prevalence and severity of the common cold?
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64
Why is fluoride commonly added to drinking water?
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65
What role does soil selenium content play in Keshan Disease?
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66
Why are adequate intakes of iodine essential to good health? What are characteristics of iodine deficiencies?
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67
What is the role of selenium in Keshan disease?
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68
What factors enhance iron absorption? What are factors that interfere with iron absorption?
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69
Which population groups would benefit the most from fluoridation of the water? Why?
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70
What factors influence copper absorption into the body?
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71
What are good dietary sources of iodine?
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72
What are consequences of a zinc deficient diet?
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73
How can a person increase their intake of dietary iron?
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74
What are the best food sources of zinc?
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75
What role does chromium play in the body?
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76
What is a goitrogen? What are common sources?
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77
How is iron transported in the blood?
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78
How iron levels maintained in the body?
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79
If the initiative does not pass and fluoride is not added to the drinking water,what are other means by which the dental health of children in the community could be protected?
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80
The water supply in the small city where you live is not fluoridated.There is an initiative on an upcoming ballot to add fluoride in small amounts to the water in order to decrease dental caries.What is your opinion on the issue?
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