Deck 10: Alterations in Immune Function

Question 1

Which disorder is associated with a type III hypersensitivity mechanism of injury?

A) Systemic lupus erythematosus
B) Graves disease
C) Erythroblastosis fetalis
D) Seasonal allergic rhinitis

Answer 1

Systemic lupus erythematosus

Question 2

Secondary immune deficiency problems may be caused by (Select all that apply.)

A) surgery.
B) high blood sugar.
C) corticosteroids.
D) genetic disorders.
E) low protein level.

Answer 2

surgery.
high blood sugar.
corticosteroids.
low protein level.

Question 3

Myasthenia gravis is a type II hypersensitivity disorder that involves

A) impaired muscle function.
B) symptoms of hyperthyroidism.
C) symptoms of arthritis or polyarthralgia.
D) symptoms of glomerular disease.

Answer 3

impaired muscle function.

Question 4

Dramatic hypotension sometimes accompanies type I hypersensitivity reactions,because

A) massive histamine release from mast cells leads to vasodilation.
B) toxins released into the blood interfere with cardiac function.
C) anaphylaxis results in large volume losses secondary to sweating.
D) hypoxia resulting from bronchoconstriction impairs cardiac function.

Question 5

An important mediator of a type I hypersensitivity reaction is

A) complement.
B) antigen-antibody immune complexes.
C) T cells.
D) histamine.

Question 6

Certain autoimmune diseases are associated with the presence of specific proteins on a person's cells.These proteins are called ________ proteins.

A) complement
B) antibody receptor
C) HLA or MHC
D) TCR or BCR

Question 7

Severe combined immunodeficiency (SCID)syndrome is an example of a(n)

A) deficient immune response.
B) excessive immune response.
C) primary acquired immunodeficiency.
D) hypersensitivity reaction.

Question 8

The hypersensitivity reaction that does not involve antibody production is type

A) I.
B) II.
C) III.
D) IV.

Question 9

Which disorder is considered a primary immunodeficiency disease?

A) HIV/AIDS
B) Malnutrition immunodeficiency
C) Cancer immunodeficiency
D) Radiation immunodeficiency

Question 10

The effects of histamine release include

A) vasoconstriction.
B) bronchodilation.
C) increased vascular permeability.
D) decreased gut permeability.

Question 11

RhoGAM (an Rh antibody)would be appropriate in an Rh-_____ woman with an _____ Rh-_____ antibody titer carrying an Rh-_____ fetus.

A) negative; positive; positive
B) positive; negative; negative
C) negative; negative; positive
D) negative; negative; negative

Question 12

Anaphylaxis may occur in certain hypersensitivity reactions,including type (Select all that apply.)

A) I.
B) II.
C) III.
D) IV.

Question 13

Seasonal allergic rhinitis is most involved in type II hypersensitivity reactions.

Question 14

The principle Ig mediator of type I hypersensitivity reactions is

A) IgA.
B) IgG.
C) IgM.
D) IgE.

Question 15

Patients with immunodeficiency disorders are usually first identified because they

A) run high fevers.
B) have unusually high WBC counts.
C) develop brain infections.
D) develop recurrent infections.

Question 16

The most common primary immune deficiency that affects only B cells is

A) DiGeorge.
B) Bruton agammaglobulinemia.
C) Wiskott-Aldrich.
D) selective IgA.

Question 17

Transfusion reactions involve RBC destruction caused by

A) donor antigens.
B) recipient antibodies.
C) donor T cells.
D) recipient T cells.

Question 18

Autoimmune diseases result from (Select all that apply.)

A) overactive immune function.
B) increase in self-tolerance.
C) failure of the immune system to differentiate self and nonself molecules.
D) communicable infections.

Question 19

A child with a history of recent strep throat infection develops glomerulonephritis.This is most likely a type _____ hypersensitivity reaction.

A) I
B) II
C) III
D) IV

Question 20

A primary effector cell of the type I hypersensitivity response is

A) monocytes.
B) mast cells.
C) neutrophils.
D) cytotoxic cells.